Name
Decoupling of PK and PD by PROTAC technology improves the therapeutic index of Bcl-xl inhibition
Daohong Zhou
Description

Discussing how PROTAC technology can be used to overcome the on-target drug platelet toxicity of Bcl-xl inhibition and can improve the therapeutic index of Bcl-xl inhibition by decoupling of PK and PD.

ASK Qs on Day 1 at 13:00 EST
(Controlling off-target degradation and monitoring toxicity)