Name
PANEL DISCUSSION: Establishing a rationale: what rules are emerging for degrader design
Date & Time
Wednesday, March 3, 2021, 10:30 AM - 11:10 AM
Speakers
Description
·· What makes a good degrader target when considering alternative degradation strategies (molecular glues/LYTACs/AUTACs etc)?
·· How can oral bioavailability be achieved?
·· What human pharmacology and dose predictions make a drug-like degrader?
·· How can in vivo work be translated to disease relevant settings and in the clinic?
·· How to choose an appropriate and effective e3 ligase?
Virtual Session Link